herbaГербариумHerbarium3034-3925ООО «ЦФА»10.33380/3034-3925-2024-1-1-9herba-5Research ArticleФАРМАЦЕВТИЧЕСКАЯ БОТАНИКАPHARMACEUTICAL BOTANYHouttuynia cordata Thunb. (Saururaceae Martinov): ботаника, этноботаника, фитохимия и биологическая активность (обзор)Houttuynia cordata Thunb. (Saururaceae Martinov): botany, ethnobotany, phytochemistry and biological activity (review)https://orcid.org/0000-0003-2129-9585АнцышкинаА. М.AntsyshkinaA. M.

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

09240, г. Москва, Устьинский проезд, д. 2/14

Alla M. Antsyshkina

8/2, Trubetskaya str., Mosсow, 119991

https://orcid.org/0000-0003-2968-2466БоковД. О.BokovD. O.

Боков Дмитрий Олегович

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

Dmitriy O. Bokov

8/2, Trubetskaya str., Mosсow, 119991

2/14, Ustyinsky proezd, Moscow, 109240

fmmsu@mail.ruhttps://orcid.org/0000-0001-7447-8881ЗайчиковаС. Г.ZaichikovaS. G.

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

Svetlana G. Zaichikova

8/2, Trubetskaya str., Mosсow, 119991

https://orcid.org/0000-0002-7731-6797ПростодушеваТ. В.ProstodushevaT. V.

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

Tatyana V. Prostodusheva

8/2, Trubetskaya str., Mosсow, 119991

https://orcid.org/0000-0002-2510-8144СтреляеваА. В.StrelyaevaA. V.

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

Angelina V. Strelyaeva

8/2, Trubetskaya str., Mosсow, 119991

https://orcid.org/0000-0002-5447-4709ФедороваЛ. В.FedorovaL. V.

19991, г. Москва, ул. Трубецкая, д. 8, стр. 2

Lyubov V. Fedorova

8/2, Trubetskaya str., Mosсow, 119991

Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет имени И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияI. M. Sechenov First MSMU of the Ministry of Health of the Russian Federation (Sechenov University)Russian FederationФедеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет имени И. М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет); Федеральное государственное бюджетное учреждение науки «Федеральный исследовательский центр питания, биотехнологии и безопасности пищи» (ФГБУН «ФИЦ питания и биотехнологии»)РоссияI. M. Sechenov First MSMU of the Ministry of Health of the Russian Federation (Sechenov University); Federal Government Budgetary Institution of Science "Federal research center of nutrition and biotechnology"Russian Federation202411102024111532Copyright © Анцышкина А.М., Боков Д.О., Зайчикова С.Г., Простодушева Т.В., Стреляева А.В., Федорова Л.В., 20242024Анцышкина А.М., Боков Д.О., Зайчикова С.Г., Простодушева Т.В., Стреляева А.В., Федорова Л.В.Antsyshkina A.M., Bokov D.O., Zaichikova S.G., Prostodusheva T.V., Strelyaeva A.V., Fedorova L.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.herbariumjournal.ru/jour/article/view/5Введение

Введение. Цель обзора – представить новые и обобщенные данные по морфологии, этноботанике, фитохимии и биологической активности Houttuynia cordata Thunb. (Saururaceae), которая используется в азиатской народной медицине в качестве лекарственного растения.

Текст

Текст. Houttuynia cordata Thunb. из рода Saururaceae – растение родом из Юго-Восточной Азии, произрастающее во влажной почве. На северо-востоке Индии его широко используют в кулинарии. Активно используется в народной медицине.

Заключение

Заключение. Фитохимический анализ растения показал, что в состав растения входят эфирные масла, терпеноиды, стероиды, фенилпропаноиды, фенолкарбоновые кислоты, гликозиды, лигнаны/неолигнаны, флавоноиды, производные фенантрена, алкалоиды и другие соединения. Представлен обзор содержания и распределения соединений-биомаркеров, а также продемонстрированы исследования экстрактов и различных выделенных соединений с широким спектром биологической активности, включая мощные противовирусные свойства (например, флавоноиды), действующих против ряда вирусов (ВПГ-1, H1N1 и DENV) и коронавирусов, таких как SARS-CoV и SARS-CoV-2. Биодоступность растительного сырья, отсутствие токсичности, широкий спектр биологической активности и терапевтический потенциал требуют дальнейшего целенаправленного изучения Houttuynia cordata для определения перспектив использования травы в качестве современного лекарственного растительного сырья.

Introduction

Introduction. The purpose of the review is to present new and summarized data on moprhology, ethnobotany, phytochemistry, and biological activity of the Houttuynia cordata Thunb. (Saururaceae), which is used in Asian folk medicine as a medical plant.

Text

Text. Houttuynia cordata Thunb. Of the genus Saururaceae – a plant native to southeast Asia that grows in moist soil. In northeast India, it’s used extensively in cooking. Actively used in folk medicine.

Conclusion

Conclusion. The phytochemical analysis of the plant showed that composition of the plant includes ethereal oils, terpenoids, steroids, phenylpropanoids, phenolcarboxylic acids, glycosides, lignans/neolignans, flavonoids, phenanthrene derivatives, alkaloids, and other compounds. There is a review of content and distribution of the biomarker compounds as well as of study of extracts and various isolated compounds of wide range of biological activities including powerful antiviral properties (such as flavonoids) acting against a range of viruses (such as HSV-1, H1N1, and DENV) and such coronaviridaes as SARS-CoV and SARS-CoV-2. Bioavailability of the plant raw materials, lack of toxicity, wide range of biological activities, and therapeutic potential require further target study of the Houttuynia cordata to determine the prospect of using of the herb as modern medicinal plant raw material.

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The authors declare that there are no conflicts of interest present.