Разработка и изучение растительной композиции, перспективной в комплексной терапии туберкулеза

Введение. Туберкулез является социально значимым заболеванием как на территории РФ, так и во всем мире. Высокая устойчивость Mycobacterium tuberculosis и высокая токсичность имеющихся химиопрепаратов обуславливают необходимость разработки новых лекарственных препаратов. Лекарственные средства растительного происхождения перспективны для комплексной терапии туберкулеза, могут поддержать ослабленный организм пациента, уменьшить побочное действие химиопрепаратов, укрепить легочную ткань.

Цель. Разработать лекарственную растительную композицию для комплексной терапии туберкулеза.

Материалы и методы. Рассмотрены 14 фармакопейных видов лекарственного растительного сырья и 3 растительные композиции на их основе. Исследования проводились по методикам Государственной фармакопеи РФ XV издания.

Результаты и обсуждение. На основании научных данных предложены 3 состава растительной композиции для комплексной терапии туберкулеза легких. Изучено количественное содержание основных групп БАВ (полисахариды, дубильные вещества, флавоноиды и аскорбиновая кислота) в 14 видах лекарственного растительного сырья и 3 составах растительных композиций. Установлен вариант растительной композиции с максимальным содержанием БАВ. Установлено взаимное влияние компонентов на выход БАВ из ЛРС.

Заключение. Разработана лекарственная растительная композиция для комплексной терапии туберкулеза, количественно определены в ней основные группы БАВ гидрофильной фракции.

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